Cancer Vaccine Works 'Startlingly Well' in Mouse Model
February 13, 2018
An experimental cancer vaccine has demonstrated dramatic results in mice with many different cancer types and distant metastases and is now to be tested in patients with cancer.
According to researchers at the Stanford University School of Medicine in California, 87 of 90 mice were cured of cancer, and among the 3 animals that experienced a recurrence, the tumors once again regressed after a second treatment.
The results were observed in mice with breast, colon, and melanoma tumors and lymphoma.
The study used an approach called in situ vaccination. With this strategy, immunoenhancing agents are injected locally into one site of tumor, which in turn triggers a local T cell immune response that will then attack the cancer cells in the rest of the body.